NURS 6501 NURS6501 NURS/6501 Knowledge check module 6 (wk 9)

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NURS 6501 NURS6501 NURS/6501 Knowledge check module 6 (wk 9)

A 21-year-old male college student was brought to Student Health Services by his girlfriend who was concerned about changes in her boyfriend’s behaviors.

The girlfriend says that recently he began hearing voices and believes everyone is out to get him. The student says he is unable to finish school because the voices told him he was not smart enough. The girlfriend relates episodes of unexpected rage and crying.

Past medical history noncontributory but family history positive for a first cousin who “had mental problems”. Denies current drug abuse but states he smoked marijuana every day during his junior and senior years of high school. He admits to drinking heavily on weekends at various fraternity houses.

Physical exam reveals thin, anxious disheveled male who, during conversations, stops talking, cocks his head and appears to be listening to something. There is poor eye contact and conversation is rambling. Based on the observed behaviors and information from girlfriend, the APRN believes the studenthas schizophrenia.

Question 1 of 4:

Describe the positive symptoms of schizophrenia and relate those symptoms to the case study patient.The positive symptoms of schizophrenia include hallucinations and delusions. Hallucinations canbe auditory, olfactory, somatic-tactile, visual, voices commenting, and voices conversing.

Delusions include being controlled, delusions of mind-reading, delusions of reference, delusions of grandiosity, guilt, persecution, somatic thought broadcasting, thought insertion and thought withdrawal. The patient in the above case study displays signs of auditory hallucinations (hearingvoices), disheveled appearance, and delusions that are persecutory.

Question 2 of 4:

Explain the genetics of schizophrenia.

Schizophrenia is a heritable disorder. Its prevalence in the general population is 1%. In monozygotic twins, its prevalence is between 30-50% and in dizygotic twins and siblings, the prevalence is around 12%, all of which are much higher than the 1% of the general population.

However, schizophrenia is not a simple genetic disorder in which inherited disease alleles will always lead to illness. Schizophrenia likely involves several genes located on different chromosomes and differs from Mendelian disorders, in which genes are fully penetrant and recognized as the primary cause of disease.

As indicated by the monozygotic concordance rate of50% in twins, the genes for schizophrenia show reduced penetrance, resulting in individuals whocarry the disease genes without manifesting the illness.

Further complicating the search for the specific genes that confer risk of schizophrenia is the variability in biologic and phenotypic traitsamong the individuals who manifest the illness. Studies are ongoing based on protein interactions may prove to be valuable in identifying novel gene associations.

NURS 6501 NURS6501 NURS/6501 Knowledge check module 6 (wk 9)

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NURS 6501 NURS6501 NURS/6501 Knowledge check module 6 (wk 9)

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A22-year-old female student was brought to her college student health department by her boyfriend. He was concerned about the changes in her behavior. The 1 2 3 4 5 Scenario 1: Schizophrenia A22-year-old female student was brought to her college student health department by her boyfriend. He was concerned about the changes 1 2 3 4 5

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